I have been on the Zone for a year.  I am a 38-year-old woman.  I have had horrible acne since I was 14 on my face and my back.  I have been on Accutane three times. Each time it worked for a while, but my acne continued to return.  I went on the Zone for weight control and, of course, it worked great!  But to me the most amazing thing was that my acne all went away within two months of starting the Zone.