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Can Epigenetic Clocks Predict Your Biological Age?

  • Barry Sears
  • Estimated read time 4 min read
  • September 18, 2025

There are two types of age: chronological and biological.  Chronological age is simple—it’s the date on your birthdate. Biological age is trickier since it depends on how…

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Categories: aging, Healthspan, Latest News

Want To Live Longer? Try Following Metabolic Engineering®.

  • Barry Sears
  • Estimated read time 6 min read
  • September 9, 2025

Calorie restriction is the only proven way to extend lifespan.  More importantly, it is also the best way to extend your healthspan, which is defined as…

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Categories: Latest News, Metabolic Engineering®, Stages of Life

GLP-1 Drugs & Heart Health: Beyond The Hype

  • Barry Sears
  • Estimated read time 6 min read
  • September 3, 2025

Drug companies are far better marketers than developers of new medical breakthroughs.  Terms like “revolutionary”, “game-changer”, or “medical breakthrough” are used as standard practice, especially since…

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Categories: GLP-1 Drugs, Heart Disease, Latest News

Ask Dr. Sears: Is There A Sugar I Can Eat To Lose Weight?

  • Barry Sears
  • Estimated read time 3 min read
  • August 5, 2025

Surprisingly, the answer is yes.  It is a natural sugar called allulose.  It has 70% of the sweetness of table sugar, but a completely different metabolic…

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Categories: diabetes, Latest News

Is A Leaky Gut Caused By Inhibition of AMPK?

  • Barry Sears
  • Estimated read time 6 min read
  • August 5, 2025

People are obsessed with gut health.  They should be, because without a healthy gut, you would be a sitting target for continual bacterial invasion from the…

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Categories: Gut Health, Latest News

The Wellness Zone Episodes

  • amillard@zoneliving.com
  • Estimated read time 1 min read
  • August 1, 2025

Welcome to The Wellness Zone Podcast hub, where Zone Diet creator Dr. Barry Sears and Mary Perry help you decode the science behind your health. Each…

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Categories: Wellness Zone Podcast

JAMA on GLP-1 Drugs—Here’s Dr. Sears’ Take

  • Barry Sears
  • Estimated read time 7 min read
  • July 29, 2025

The Journal of the American Medical Association recently published an article on tips for using GLP-1 drugs (1).  Are these tips valid?  Let’s find out? First,…

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Categories: GLP-1 Drugs, Latest News

Stopping GLP-1 Drugs May Increase Cardiovascular Risk

  • Barry Sears
  • Estimated read time 9 min read
  • July 29, 2025

Everyone wants to lose excess body fat.  However, the Holy Grail of weight loss is losing excess body fat while maintaining, if not increasing, lean body…

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Categories: GLP-1 Drugs, Heart Disease, Latest News

How Metabolic Engineering® Reduces Inflammation

  • Barry Sears
  • Estimated read time 7 min read
  • July 23, 2025

Inflammation is a crucial component of our metabolism that keeps us alive.  It is our initial defense against microbial invasion or physical injury. However, unless we turn…

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Categories: Inflammation, Latest News, Metabolic Engineering®

NY Times on Sugar: Here’s What They Missed

  • Barry Sears
  • Estimated read time 6 min read
  • July 22, 2025

Last year, the NY Times had an article entitled This Is Your Body on Sugar (1).   I thought this might be a good time to…

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Categories: Ask Dr. Sears, Latest News

What’s the Best Way To Determine My Percentage of Body Fat?

  • Barry Sears
  • Estimated read time 4 min read
  • July 15, 2025

Excess body fat is strongly related to increased cardiovascular disease and mortality.  The gold standard for measuring your percentage of body fat has always been underwater…

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Categories: Latest News, Obesity, Zone Science

Why Prediabetes Is America’s Most Dangerous Silent Epidemic

  • Barry Sears
  • Estimated read time 7 min read
  • July 14, 2025

It may not get the headlines, but it has the potential to destroy our health care system in a few decades.  What is this new epidemic? …

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Categories: chronic diseases, diabetes, Latest News
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