Ask Dr. Sears: Why Are Diet Definitions So Confusing?
I believe the primary reason for dietary confusion is that different diets are defined more by philosophy rather than science. This can be overcome by: (a)…
Read More
The Science of the Zone
Latest News
Why Metabolic Engineering?
Featured Categories
It Starts With The Zone Diet
30 Years of The Zone
View All
Live Your Life To The Fullest In The Zone
Wellness is a lifelong commitment. It begins in the womb and goes through the continuum of life. The…
What Is The Zone?
The Zone is the physiological state when your metabolism performs at peak efficiency. Metabolism keeps us alive by…
Benefits Of Being In The Zone
The health benefits of being in the Zone are numerous. Here is a small listing of those benefits: AMPK…
Evolution Of The Zone
For the past 40 years, I have been exploring the mysteries of metabolism and how diet can control…
GLP-1 Drugs
Ozempic Weight Loss Fever
Americans are increasingly desperate to lose weight as our national obesity rate increases. The current mania for injectable…
What Is AMPK?
Defining Anti-Inflammatory Diets
To make science reproducible, you must have definitions. The more rigorous the description, the more likely the science…
Insulin Resistance
How Poor Sleep Wrecks Your Metabolism (and How to Fix It)
Poor Sleep & Your Metabolism: How Quality Sleep Impacts Your Body Think sleep is all about the hours…
Stages of Life
How Many Calories Do I Cut To Activate AMPK?
Want to slow aging and boost metabolism? Cutting calories is key—but how much is too much? In this…
More on Metabolism
Ask Dr. Sears: Is the Zone Diet Still Ahead of Its Time?
Before I introduced the Zone diet in 1995, dietary advice was essentially like a Miller Lite commercial. On one side, you had those screaming that fat makes…
Read MoreCan Metabolic Engineering Slow Prostate Cancer Growth?
All cancers are ultimately driven by metabolic disruption. If that is the case, can Metabolic Engineering® be used slow down tumor growth? If so, this would…
Read MoreThe Dark Side of GLP-1 Drugs (and Why Metabolic Engineering is Better)
GLP-1 drugs restrict calorie intake, leading to rapid metabolic benefits. So does Metabolic Engineering®. The critical question is whether those benefits can be sustained long-term without…
Read MoreThe New Food Pyramid: The Good, the Bad, and the Ignored
The new USDA Food Pyramid was recently released. Besides the graphic description of the new recommendations that looks like a Jackson Pollock painting, is there anything…
Read MoreChronic Stress and Inflammation: The Key Role of AMPK
Over 75% of Americans report symptoms of stress. So, what exactly is stress biochemically, and more importantly, how can you reduce it? Stress is the…
Read MoreWhat Really Causes AFib?
Atrial fibrillation (Afib) is the most common form of cardiac arrhythmia. It is known that Afib is associated with an increased risk of stroke, heart failure,…
Read MoreHow Long Can a Person Fast?
The human body is very fragile. You can go without breathing for about three minutes. You can go without water for about three days. Beyond those…
Read MoreNew Miracle “Drug” to Reduce Mortality in Kidney Dialysis Patients
Going on kidney dialysis is essentially a death sentence, as the death rate is about 20 percent per year. Of those deaths, accelerated cardiovascular disease accounts…
Read MoreCan Metabolic Engineering Treat Alzheimer’s?
Effectively treating Alzheimer’s disease has been one of the most significant failures of the pharmacological industry. Yet Alzheimer’s can be viewed as a metabolic disorder driven…
Read MoreAsk Dr. Sears: How Do You Define Obesity?
When the Supreme Court Justice Potter Stewart was asked how he defined hard-core pornography, he stated, “I know it when I see it”. The same might…
Read MoreWhat Really Causes Obesity?
There is no doubt that obesity is on the rise. But why? Is it because we are not exercising enough? Or are we simply overeating? Obviously,…
Read More