Metabolism is how we convert food into energy to keep us alive.  It also controls your immune system, inflammation, repair of damaged tissue, and your rate of aging. 

The master regulator of metabolism is an ancient enzyme known as AMPK.  If AMPK activity is optimized, you live longer.  If AMPK activity is inhibited, you gain weight, develop various chronic diseases at an earlier age, and accelerate your rate of aging.  When you are in the Zone, your levels of AMPK are optimal to achieve a longer and better life.  More importantly, AMPK activity is under robust dietary control. 

Metabolism is too complex and dynamic to be controlled by a drug.  Drugs act like a light switch that turns a single enzyme or receptor on or off.  Metabolism is like a mixing board in a studio that the sound engineer must constantly balance.  This is especially true for AMPK, with your diet acting as the sound engineer.  You must keep AMPK in a zone to maintain an efficient metabolism.  This is also true for removing a growing population of senescent cells that are the underlying cause of aging and the development of chronic diseases associated with aging.   Senescent cells are transformed cells like cancer cells.  Instead of growing uncontrollably, senescent cells now generate new sources of inflammation inside the body that speed up aging by increasing the levels of inflammation in every organ in your body.

Furthermore, senescent cells can turn other cells into new senescent cells.  In this regard, senescent cells are often called “zombie cells .” 

Under normal conditions, your immune system quickly eliminates these senescent cells.  However, if AMPK activity is not optimal, the ability of the immune system to remove these zombie cells is compromised, and their population begins to grow.

Any increase in zombie cells accelerates aging and the earlier appearance of the chronic diseases associated with aging, as shown below:

You can reprogram your immune system using Metabolic Engineering®  to recognize and eliminate senescent cells more effectively by optimizing AMPK.  As you age, AMPK activity decreases, and the population of senescent cells begins to grow.  Metabolic Engineering® was developed to reduce the levels of senescent cells by increasing the activity of AMPK inside each of your 30 trillion cells.  

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