The Wellness Zone Podcast with Dr. Barry Sears and Mary Perry

Did you know Alzheimer’s disease is often called “type 3 diabetes”? That’s because of its strong connection to insulin resistance.

When insulin resistance impacts the brain, it struggles to generate energy from glucose, putting essential cellular functions at risk. As a result, the brain has a harder time clearing harmful protein aggregates linked to Alzheimer’s, leading to oxidative stress, neuroinflammation, and eventually, the loss of cognitive function.

Here’s the reality: there’s no approved drug to treat Alzheimer’s. But there’s good news—your diet can play a crucial role in prevention. Reducing insulin resistance may be one of the most powerful ways to protect your brain. That’s where Metabolic Engineering® comes in.

In this episode, join Mary Perry and me to learn how this groundbreaking dietary approach can help lower your risk of cognitive decline and keep your brain healthier for years to come. 00:00 Intro 01:16 The dramatic rise in insulin resistance throughout our population 02:09 Are there drugs to treat Alzheimer’s? 3:32 What obesity, diabetes and Alzheimers all have in common 4:49 Why activating AMPK is so important. 5:20 Improving production of ATP 7:25 How Metabolic Engineering reduces inflammation 9:17 Blood tests to see if inflammation is reducing, like HOMA-IR, triglycerides to HDL cholesterol.