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  • Stages of Life

Category: Stages of Life

Can Epigenetic Clocks Predict Your Biological Age?

  • Barry Sears
  • Estimated read time 4 min read
  • September 18, 2025

There are two types of age: chronological and biological.  Chronological age is simple—it’s the date on your birthdate. Biological age is trickier since it depends on how…

Categories: aging, Healthspan, Latest News

Want To Live Longer? Try Following Metabolic Engineering®.

  • Barry Sears
  • Estimated read time 6 min read
  • September 9, 2025

Calorie restriction is the only proven way to extend lifespan.  More importantly, it is also the best way to extend your healthspan, which is defined as…

Categories: Latest News, Metabolic Engineering®, Stages of Life

Brain Fog and your Metabolism

  • Barry Sears
  • Estimated read time 1 min read
  • March 17, 2025

Ever feel like your brain just isn’t firing on all cylinders? That’s brain fog—when your brain struggles to produce enough energy to function at its best.…

Categories: aging, Healthspan, Stages of Life

How Many Calories Do I Cut To Activate AMPK?

  • Barry Sears
  • Estimated read time 1 min read
  • March 17, 2025

Want to slow aging and boost metabolism? Cutting calories is key—but how much is too much? In this video, Dr. Barry Sears explains the science behind…

Categories: aging, Ask Dr. Sears, Stages of Life

The #1 Factor for a Longer Life (It’s NOT Your Genes!)

  • Barry Sears
  • Estimated read time 1 min read
  • March 4, 2025

What’s the secret to living longer—your genes or your lifestyle? 🤔 The answer is clear: lifestyle wins. While you may have 20,000 genes in your DNA,…

Categories: aging, Ask Dr. Sears, Stages of Life

Calorie Restriction: The 500-Year-Old Secret to Longevity

  • Barry Sears
  • Estimated read time 1 min read
  • February 17, 2025

Can eating less help you live longer? The idea dates back to the 16th century when Venetian nobleman Luigi Cornaro transformed his health with a strict,…

Categories: aging, Ask Dr. Sears, Benefits of Metabolic Engineering

Microplastics Are Everywhere—And They Might Be Destroying Your Brain

  • Barry Sears
  • Estimated read time 1 min read
  • February 17, 2025

Microplastics are everywhere—and they’re making their way into your body. From the water you drink to the food you eat, these tiny plastic particles are nearly…

Categories: auto immune disease, chronic diseases, Healthspan

Low Energy? The Truth About Metabolism

  • Barry Sears
  • Estimated read time 1 min read
  • January 30, 2025

Ever wonder why you feel drained—physically or mentally? It all comes down to metabolism. Your body runs on ATP, the energy currency that fuels everything from…

Categories: Ask Dr. Sears, Insulin Resistance, Metabolic Engineering®

Healthspan vs Lifespan

  • Barry Sears
  • Estimated read time 1 min read
  • January 9, 2025

What matters more: how long or how well you live? While lifespan measures total years, healthspan focuses on the quality of those years spent in good…

Categories: aging, Ask Dr. Sears, Healthspan

Will Rapamycin Make Me Live Longer?

  • Barry Sears
  • Estimated read time 1 min read
  • November 19, 2024

Is Rapamycin the key to living longer? While it’s a cancer drug, Rapamycin is getting attention for its potential longevity benefits by decreasing mTOR activity and…

Categories: aging, Ask Dr. Sears, cancer
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DrSears.com is the science site for the Zone. DrSears.com will help you stay updated on the rapidly changing scientific landscape of the role of nutrition to optimize the Resolution Response that is necessary to maintain optimal wellness in every stage of life.

Disclaimer: The contents of this website are based on the opinions of Dr. Barry Sears unless otherwise noted. ndividual articles are based upon the opinions of Dr. Barry Sears, who retains the copyright as marked. The information on this website is not intended to replace a relationship with a qualified healthcare professional and is not intended as medical advice. It is intended as a sharing of the knowledge and information from the research and experience of Dr. Barry Sears. Dr. Barry Sears encourages you to make your own healthcare decisions based on your research and in partnership with a qualified healthcare professional.

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