Zone Science

What is the Zone?

The Zone is the physiological state when your metabolism performs at peak efficiency.
Metabolism keeps us alive by converting food into chemical energy, maintaining the
immune system, controlling inflammation, repairing damaged tissue from external and
internal injuries, and resisting microbial invasions. Meeting those requirements requires
constant dynamic control of gene activation. The master switch in every cell that
regulates those genes is AMPK, which is under robust dietary control.

The Zone is not some mystical state. There are blood markers that define it. Either you
are in the Zone, or you are not. If those blood markers are in their appropriate range,
your body works at peak metabolic efficacy.  Thus, being in the Zone becomes the
medical definition of wellness. On the other hand, if you are not in the Zone, your
metabolic efficacy is compromised, leading to excess body fat accumulation, reduced
physical and mental performance, earlier development of chronic disease, and the
acceleration of aging.

No drug can get you to the Zone. On the other hand, the lifelong use of Metabolic
Engineering® can get you the Zone. Metabolic Engineering® is a clinically proven
dietary technology that maintains AMPK in the therapeutic zone that defines wellness.
The benefit to you is a longer and better life.


Explore a treasure trove of articles and videos curated by Dr. Barry Sears, the renowned pioneer in nutritional science and creator of the Zone Diet. Uncover how your dietary choices impact your health, from balancing macronutrients and micronutrients to using food as a tool for disease prevention.

You’ll gain the knowledge to make informed decisions and take control of your well-being. Ready to transform your health? Start watching now and let Dr. Sears guide you on your journey to better nutrition and wellness!

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