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Tag: metabolic engineering

Can Epigenetic Clocks Predict Your Biological Age?

  • Barry Sears
  • Estimated read time 6 min read
  • September 18, 2025

Key Takeaways Chronological Age vs Biological Age There are two types of age: chronological and biological.  Chronological age is simple—it’s the date on your birthdate. Biological age…

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Categories: aging, Healthspan, Latest News

Calorie Restriction and Longevity: Why Metabolic Engineering® May Help You Live Longer

  • Barry Sears
  • Estimated read time 7 min read
  • September 9, 2025

Key Takeaways Calorie restriction is the only proven way to extend lifespan.  More importantly, it is also the best way to extend your healthspan, which is…

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Categories: Latest News, Metabolic Engineering®, Stages of Life

Do GLP-1 Drugs Really Reduce Heart Attack Risk?

  • Barry Sears
  • Estimated read time 8 min read
  • September 3, 2025

Key Takeaways Drug companies are far better marketers than developers of new medical breakthroughs.  Terms like “revolutionary”, “game-changer”, or “medical breakthrough” are used as standard practice,…

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Categories: GLP-1 Drugs, Heart Disease, Latest News

What Causes Leaky Gut? The Role of AMPK in Gut Barrier Health

  • Barry Sears
  • Estimated read time 8 min read
  • August 5, 2025

Key Takeaways What Is Metabolic Endotoxemia? People are obsessed with gut health.  They should be, because without a healthy gut, you would be a sitting target…

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Categories: Gut Health, Latest News

GLP-1 Drugs for Weight Loss: Dr. Barry Sears Responds to JAMA Guidelines

  • Barry Sears
  • Estimated read time 8 min read
  • July 29, 2025

Key Takeaways The Journal of the American Medical Association recently published an article on tips for using GLP-1 drugs (1).  Are these tips valid?  Let’s find…

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Categories: GLP-1 Drugs, Latest News

How Metabolic Engineering® Helps Reduce Chronic Inflammation

  • Barry Sears
  • Estimated read time 9 min read
  • July 23, 2025

Key Takeaways Why Inflammation Is Both Necessary and Dangerous Inflammation is a crucial component of our metabolism that keeps us alive.  It is our initial defense…

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Categories: Inflammation, Latest News, Metabolic Engineering®

Why Prediabetes Is America’s Most Dangerous Silent Epidemic (And How to Reverse Insulin Resistance)

  • Barry Sears
  • Estimated read time 9 min read
  • July 14, 2025

Key Takeaways It may not get the headlines, but it has the potential to destroy our health care system in a few decades.  What is this…

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Categories: chronic diseases, diabetes, Latest News

Ask Dr. Sears: Everything You Wanted to Know About HbA1c (But Didn’t Want to Google)

  • Barry Sears
  • Estimated read time 11 min read
  • June 13, 2025

Key Takeaways A major women’s magazine recently asked me some questions on HbA1c.  Here are my answers: Why is HbA1C an important metric for blood sugar…

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Categories: Ask Dr. Sears, Latest News

Understanding Wellness: Simple Blood Tests That Measure Your Health

  • Barry Sears
  • Estimated read time 8 min read
  • June 13, 2025

Wellness is a medical condition, just like diabetes, heart disease, or any other chronic condition. What links wellness with chronic disease is your current state of…

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Categories: Healthspan, Latest News, Zone Science

Do I Need Amino Acids Supplements?

  • Barry Sears
  • Estimated read time 4 min read
  • June 3, 2025

Protein supplements are everywhere—but are they really necessary?  Dr. Sears explains why getting the right amount of protein from whole foods is often better than relying…

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Categories: Zone Science

The Zone Diet and Brain Health: How to Fuel Peak Mental Performance

  • Barry Sears
  • Estimated read time 1 min read
  • June 3, 2025

Your brain runs on energy—and if it’s not getting enough, it simply can’t function at full capacity. In this video, Dr. Barry Sears explains how brain…

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Categories: Latest News, Zone Science

Are Liver Detoxes a Scam? Here’s What Actually Works

  • Barry Sears
  • Estimated read time 1 min read
  • May 27, 2025

You’ve probably seen liver detox teas, cleanses, or fasts all over the internet—but do they actually work? Dr. Barry Sears, creator of the Zone Diet and…

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Categories: detoxing, Fatty Liver Disease, Zone Science
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