Insulin resistance is a key factor in many health issues, and measuring it doesn’t always require expensive tests. The triglyceride (TG) to high-density lipoprotein cholesterol (HDL) ratio, commonly included in routine blood work, serves as a reliable surrogate marker. Insulin resistance is often linked to increased body fat, with its earliest effects showing in the liver, where dietary fats are repackaged into lipoproteins. As insulin resistance develops, triglyceride levels rise, HDL decreases, and LDL particles become smaller and denser.

Topics discussed:

00:00 How do you define Wellness?

01:12 Understanding the HOMA-IR blood test

02:36 What causes insulin Resistance is inflammation

03:42 Chronic diseases caused by insulin resistance

04:38 Why Americans don’t consume enough protein, or eat the right balance of carbs and fats.

05:08 Metabolic Engineering and treating food like a drug

06:45 Managing diet, exercise, and stress reduction—the 80-15-5 rule