Dietary Guidelines for Metabolic Engineering™

  • Overview
  • Role of the Zone diet to reduce insulin resistance
  • Calorie restriction slows the rate of aging caused by insulin resistance
  • Link of insulin resistance and AMPK inhibition
  • Protein requirements
  • Macronutrient balance
  • Calorie intake
  • Calorie intake
  • Role of omega-3 fatty acids to resolve inflammation that causes insulin resistance
  • Reduction of inflammation
  • Increasing resolution
  • Activation of AMPK
  • Role of polyphenols to repair the damage caused by insulin resistance
  • Activation of AMPK and Nrf2
  • Meal timing
  • Circadian rhythms
  • Personalizing Metabolic Engineering™
  • Blood markers
  • Overall success in reducing insulin resistance: HOMA-IR
  • Optimizing the Zone diet: TG/HDL ratio
  • Optimizing Omega-3 intake: AA/EPA ratio
  • Optimizing Polyphenol intake: HbA1c
  • Other lifestyle interventions to reduce insulin resistance
  • 80-15-5 Rule for Diet: Exercise: Stress reduction