Metabolic Engineering®: An Overview

Metabolic Engineering® is clinically proven technology to reduce insulin resistance by activating AMPK in each of your 30 trillion cells.  Metabolic Engineering® is not a magic bullet but an orchestration of various dietary inputs that are necessary to maintain an efficient metabolism, as shown below:

The first thing to notice is that these dietary inputs are different in importance, but they still need to work together as a team to reduce insulin resistance by activating AMPK.

Calorie restriction without malnutrition is the most powerful dietary technology to activate  AMPK.   The Zone diet accomplishes that goal without hunger or fatigue due to its patented macronutrient composition to reduce elevated insulin (i.e., hyperinsulinemia).  This is why the Zone diet is the foundation of Metabolic Engineering®.

However, you will need more than the Zone diet to get to the Zone and slow down aging. You will also need adequate omega-3 fatty acids to resolve the inflammation caused by insulin resistance and sufficient polyphenols to repair the damage caused by insulin resistance. Omega-3 fatty acids and polyphenols are critical for success because they indirectly activate AMPK.  If adequate omega-3 fatty acids and polyphenols are not part of your current diet, then reaching the Zone to slow down aging will be far more difficult than it should be.

However, without the Zone diet as your dietary foundation, even the ideal level of supplementation with purified omega-3 fatty acids and polyphenol extracts will not generate the necessary level of AMPK activation to eliminate senescent cells that accelerate aging.

The first thing to notice is that these dietary inputs are different in importance, but they still need to work together as a team to reduce insulin resistance by activating AMPK.

Calorie restriction without malnutrition is the most powerful dietary technology to activate  AMPK.   The Zone diet accomplishes that goal without hunger or fatigue due to its patented macronutrient composition to reduce elevated insulin (i.e., hyperinsulinemia).  This is why the Zone diet is the foundation of Metabolic Engineering®.

However, you will need more than the Zone diet to get to the Zone and slow down aging. You will also need adequate omega-3 fatty acids to resolve the inflammation caused by insulin resistance and sufficient polyphenols to repair the damage caused by insulin resistance. Omega-3 fatty acids and polyphenols are critical for success because they indirectly activate AMPK.  If adequate omega-3 fatty acids and polyphenols are not part of your current diet, then reaching the Zone to slow down aging will be far more difficult than it should be.

However, without the Zone diet as your dietary foundation, even the ideal level of supplementation with purified omega-3 fatty acids and polyphenol extracts will not generate the necessary level of AMPK activation to eliminate senescent cells that accelerate aging.

Click here for The Role of the Zone Diet in Metabolic Engineering®

You May Also Like

1 comment

Kristen Freed says:

How am I just learning about this now? Metabolic Engineering? Apparently I’ve been throwing away the materials that I receive with my fish oils and Polyphenols. Clearly a baby with the bathwater type situation. I’m still thinking that a CGM might also be a useful tool in determining whether or not one is in the zone or not. The blood test is too expensive to use on a regular basis. I bought one to evaluate my hypothesis but I haven’t gotten around to using it yet. It is now being recommended for migraineurs to alert us when our blood sugar is dipping too low, akin to the fuel light in a car. Granted setting an alarm on one’s watch every five hours to remind one to eat might work, but in many professions, such as waiting tables, it’s easy to get caught up and realize you done it yet again, given yourself a migraine by going too long without eating (skipping meals being a significant trigger). A CGM can be set to give an alert to one’s iPhone or Apple Watch allowing enough time to go find food before running out of gas. Gas in this instance being blood sugar. The ‘gas’ that the brain runs on. Anyway, eager to learn more. Will add to the to do list.

Leave a Reply

Your email address will not be published. Required fields are marked *