Metabolic Engineering® is clinically proven technology to reduce insulin resistance by activating AMPK in each of your 30 trillion cells.  Metabolic Engineering™ is not a magic bullet but an orchestration of various dietary inputs that are necessary to maintain an efficient metabolism, as shown below:

The first thing to notice is that these dietary inputs are different in importance, but they still need to work together as a team to reduce insulin resistance by activating AMPK.

Calorie restriction without malnutrition is the most powerful dietary technology to activate  AMPK.   The Zone diet accomplishes that goal without hunger or fatigue due to its patented macronutrient composition to reduce elevated insulin (i.e., hyperinsulinemia).  This is why the Zone diet is the foundation of Metabolic Engineering®.

However, you will need more than the Zone diet to get to the Zone and slow down aging. You will also need adequate omega-3 fatty acids to resolve the inflammation caused by insulin resistance and sufficient polyphenols to repair the damage caused by insulin resistance. Omega-3 fatty acids and polyphenols are critical for success because they indirectly activate AMPK.  If adequate omega-3 fatty acids and polyphenols are not part of your current diet, then reaching the Zone to slow down aging will be far more difficult than it should be.

However, without the Zone diet as your dietary foundation, even the ideal level of supplementation with purified omega-3 fatty acids and polyphenol extracts will not generate the necessary level of AMPK activation to eliminate senescent cells that accelerate aging.

The first thing to notice is that these dietary inputs are different in importance, but they still need to work together as a team to reduce insulin resistance by activating AMPK.

Calorie restriction without malnutrition is the most powerful dietary technology to activate  AMPK.   The Zone diet accomplishes that goal without hunger or fatigue due to its patented macronutrient composition to reduce elevated insulin (i.e., hyperinsulinemia).  This is why the Zone diet is the foundation of Metabolic Engineering®.

However, you will need more than the Zone diet to get to the Zone and slow down aging. You will also need adequate omega-3 fatty acids to resolve the inflammation caused by insulin resistance and sufficient polyphenols to repair the damage caused by insulin resistance. Omega-3 fatty acids and polyphenols are critical for success because they indirectly activate AMPK.  If adequate omega-3 fatty acids and polyphenols are not part of your current diet, then reaching the Zone to slow down aging will be far more difficult than it should be.

However, without the Zone diet as your dietary foundation, even the ideal level of supplementation with purified omega-3 fatty acids and polyphenol extracts will not generate the necessary level of AMPK activation to eliminate senescent cells that accelerate aging.

Click here for The Role of the Zone Diet in Metabolic Engineering®