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Category: Metabolic Engineering®

What Controls Your Metabolism? The Balance of AMPK and mTOR Explained

  • Barry Sears
  • Estimated read time 7 min read
  • March 3, 2026

Key Takeaways Metabolism is incredibly complex. It is dynamic and governed by a highly sophisticated series of interlocking feedback mechanisms to keep it in a zone…

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Categories: Latest News, Metabolic Engineering®

Why Diet Definitions Are So Confusing: Understanding Macronutrients, Calories, and the Zone Diet

  • Barry Sears
  • Estimated read time 6 min read
  • February 26, 2026

Key Takeaways Diet definitions are confusing because most diets are defined by philosophy rather than science. A clearer way to define a diet is by three…

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Categories: Latest News, Metabolic Engineering®, Zone Science

Is the Zone Diet Still Ahead of Its Time? The Science Behind Metabolic Control

  • Barry Sears
  • Estimated read time 6 min read
  • January 30, 2026

Key Takeaways Yes—the Zone Diet may still be ahead of its time. Unlike most diet trends that focus on eliminating a single nutrient, the Zone Diet…

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Categories: Ask Dr. Sears, Latest News, Metabolic Engineering®

Can Metabolic Engineering Slow Prostate Cancer Growth?

  • Barry Sears
  • Estimated read time 8 min read
  • January 22, 2026

Key Takeaways • Prostate cancer progression is strongly influenced by chronic inflammation and metabolic dysfunction. A recent clinical study found that omega-3 supplementation and calorie reduction…

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Categories: chronic diseases, Latest News, Metabolic Engineering®

GLP-1 Weight Loss Drugs: Risks, Rebound Weight Gain, and a Metabolic Engineering Alternative

  • Barry Sears
  • Estimated read time 8 min read
  • January 22, 2026

Key Takeaways GLP-1 drugs restrict calorie intake, leading to rapid metabolic benefits.  So does Metabolic Engineering®. The critical question is whether those benefits can be sustained…

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Categories: Ask Dr. Sears, GLP-1 Drugs, Latest News

Long COVID and Metabolism: How AMPK Activation May Reduce Risk

  • Barry Sears
  • Estimated read time 7 min read
  • September 23, 2025

Key Takeaways It has been nearly five years since COVID-19 first appeared.  However, for many, the consequences of initial infection remain with them for years.  About…

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Categories: Latest News, Metabolic Engineering®

Calorie Restriction and Longevity: Why Metabolic Engineering® May Help You Live Longer

  • Barry Sears
  • Estimated read time 7 min read
  • September 9, 2025

Key Takeaways Calorie restriction is the only proven way to extend lifespan.  More importantly, it is also the best way to extend your healthspan, which is…

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Categories: Latest News, Metabolic Engineering®, Stages of Life

How Metabolic Engineering® Reduces Inflammation

  • Barry Sears
  • Estimated read time 7 min read
  • July 23, 2025

Inflammation is a crucial component of our metabolism that keeps us alive.  It is our initial defense against microbial invasion or physical injury. However, unless we turn…

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Categories: Inflammation, Latest News, Metabolic Engineering®

Rocket Fuel for Longevity: Inside the Metabolic Engineering Plan

  • Barry Sears
  • Estimated read time 1 min read
  • March 25, 2025

Want to take control of your metabolism and improve your long-term health? Reversing insulin resistance is only the first step. The real secret lies in activating…

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Categories: Latest News, Metabolic Engineering®, Metabolism

The #1 Factor for a Longer Life (It’s NOT Your Genes!)

  • Barry Sears
  • Estimated read time 1 min read
  • March 11, 2025

What’s the secret to living longer—your genes or your lifestyle? 🤔 The answer is clear: lifestyle wins. While you may have 20,000 genes in your DNA,…

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Categories: aging, Ask Dr. Sears, Healthspan

Polyphenols Explained: How They Affect Your Genes and Health

  • Barry Sears
  • Estimated read time 1 min read
  • March 11, 2025

Polyphenols do more than just give fruits and vegetables their vibrant colors—they have the potential to influence your genes. That’s right, the food you eat can…

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Categories: Latest News, Metabolic Engineering®, Metabolism

The Science of Athletic Performance: How Energy, Focus & Metabolism Shape Success

  • Barry Sears
  • Estimated read time 1 min read
  • March 4, 2025

What’s the secret to peak athletic performance? It all comes down to two key factors: energy production and focus. ATP is the fuel that powers muscle…

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Categories: athletic performance, Latest News, Metabolic Engineering®
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