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Category: Zone Science

Information supporting the Zone as the physiological state when your metabolism performs at peak efficiency.

How Zone Foods Activate AMPK

  • Barry Sears
  • Estimated read time 1 min read
  • November 21, 2024

The most effective way to activate AMPK is by calorie restriction.  Once AMPK is activated, you burn fat faster, improve metabolic efficiency, and slow down aging. …

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Categories: Ask Dr. Sears, What Is AMPK?, Zone Foods

How AMPK Reduces Inflammation

  • Barry Sears
  • Estimated read time 1 min read
  • November 19, 2024

AMPK might sound like just another scientific buzzword, but it’s one of the most powerful tools your body has to fight inflammation. So how does it…

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Categories: Ask Dr. Sears, Featured Metabolism Posts, Inflammation

Why Omega-3 Studies Fall Short: Problems With Analysis

  • Barry Sears
  • Estimated read time 6 min read
  • November 14, 2024

A recent article has been published stating that EPA is superior to combinations of EPA and DHA in treating cardiovascular disease (1). The conclusion was drawn based on analyzing…

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Categories: Zone Science

Zone Diet vs The Mediterranean Diet: The Insulin Resistance Challenge

  • Barry Sears
  • Estimated read time 7 min read
  • November 14, 2024

Insulin resistance is the driving factor for many chronic disease states, including obesity, diabetes, heart disease, and Alzheimer’s.  Yet the level of insulin resistance in each of…

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Categories: Latest News, Zone Science

Evolution Of The Zone

  • Barry Sears
  • Estimated read time 8 min read
  • November 13, 2024

For the past 40 years, I have been exploring the mysteries of metabolism and how diet can control metabolic efficiency.   Why?  Metabolism controls every aspect of…

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Categories: 30 Years of The Zone, Zone Science

Benefits Of Being In The Zone

  • Barry Sears
  • Estimated read time 1 min read
  • November 13, 2024

The health benefits of being in the Zone are numerous.  Here is a small listing of those benefits: AMPK activation: Your overall ability to repair tissue damage…

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Categories: 30 Years of The Zone, Zone Science

Measuring Wellness

  • Barry Sears
  • Estimated read time 2 min read
  • November 12, 2024

How can you tell if you are in the Zone?  Your blood will tell.  It is impossible to measure AMPK without a tissue biopsy.  However, a…

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Categories: home tests, Resources, tests

What Is The Zone?

  • Barry Sears
  • Estimated read time 2 min read
  • November 12, 2024

The Zone is the physiological state when your metabolism performs at peak efficiency. Metabolism keeps us alive by converting food into chemical energy, maintaining the immune…

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Categories: 30 Years of The Zone, Zone Science

Senolytic Nutrition and the Molecular Biology of Wellness

  • Barry Sears
  • Estimated read time 7 min read
  • November 28, 2022

There are two sides to medicine.  One side is treating disease; the other side is maintaining wellness.  We currently define disease by its symptoms and then…

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Categories: Zone Science

EPA and DHA: The Science Behind Why You Need Both Omega-3s In Your Diet

  • Barry Sears
  • Estimated read time 9 min read
  • June 23, 2020

The primary benefits of omega-3s come from their ability to resolve inflammation through the hormones they generate. The two omega-3s that have been the most widely studied for…

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Categories: chronic diseases, Metabolic Engineering®, Metabolism

Managing Covid-19 with Pro-Resolution Nutrition

  • Barry Sears
  • Estimated read time 15 min read
  • April 15, 2020

In my previous blog, I discussed the realities of the coronavirus pandemic.  As a quick recap, the coronavirus (SARS-CoV-2) is here to stay.  That means it will be…

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Categories: chronic diseases, Zone Science

Some Inconvenient Facts About Omega-3 Fatty Acids in Heart Disease and Prostate Cancer

  • Barry Sears
  • Estimated read time 7 min read
  • March 18, 2020

Two recent meta-analysis studies published by the same lead author have stated the conclusion that omega-3 fatty acids have little, if any, benefit in treating cardiovascular…

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Categories: cancer, chronic diseases, Heart Disease
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