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Tag: AMPK

What Controls Your Metabolism? The Balance of AMPK and mTOR Explained

  • Barry Sears
  • Estimated read time 7 min read
  • March 3, 2026

Key Takeaways Metabolism is incredibly complex. It is dynamic and governed by a highly sophisticated series of interlocking feedback mechanisms to keep it in a zone…

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Categories: Latest News, Metabolic Engineering®

Why Diet Definitions Are So Confusing: Understanding Macronutrients, Calories, and the Zone Diet

  • Barry Sears
  • Estimated read time 6 min read
  • February 26, 2026

Key Takeaways Diet definitions are confusing because most diets are defined by philosophy rather than science. A clearer way to define a diet is by three…

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Categories: Latest News, Metabolic Engineering®, Zone Science

Is the Zone Diet Still Ahead of Its Time? The Science Behind Metabolic Control

  • Barry Sears
  • Estimated read time 6 min read
  • January 30, 2026

Key Takeaways Yes—the Zone Diet may still be ahead of its time. Unlike most diet trends that focus on eliminating a single nutrient, the Zone Diet…

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Categories: Ask Dr. Sears, Latest News, Metabolic Engineering®

GLP-1 Weight Loss Drugs: Risks, Rebound Weight Gain, and a Metabolic Engineering Alternative

  • Barry Sears
  • Estimated read time 8 min read
  • January 22, 2026

Key Takeaways GLP-1 drugs restrict calorie intake, leading to rapid metabolic benefits.  So does Metabolic Engineering®. The critical question is whether those benefits can be sustained…

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Categories: Ask Dr. Sears, GLP-1 Drugs, Latest News

How Chronic Stress Causes Inflammation: The Role of AMPK

  • Barry Sears
  • Estimated read time 4 min read
  • December 2, 2025

Key Takeaways Over 75% of Americans report symptoms of stress. So, what exactly is stress biochemically, and more importantly, how can you reduce it?   Stress…

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Categories: Inflammation, Latest News, What Is AMPK?

What Causes AFib? The Role of Inflammation and AMPK

  • Barry Sears
  • Estimated read time 11 min read
  • December 2, 2025

Key Takeaways Atrial fibrillation (Afib) is the most common form of cardiac arrhythmia.  It is known that Afib is associated with an increased risk of stroke,…

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Categories: Heart Disease, Latest News

Omega-3 Fatty Acids Reduce Cardiovascular Death in Dialysis Patients

  • Barry Sears
  • Estimated read time 7 min read
  • November 18, 2025

Key Takeaways Can Omega-3 Fatty Acids Reduce Mortality in Dialysis Patients? Quick Answer Yes. A clinical study of more than 1,200 kidney dialysis patients found that…

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Categories: Kidney, Latest News

Alzheimer’s Disease and Insulin Resistance: Can Metabolic Engineering Help?

  • Barry Sears
  • Estimated read time 6 min read
  • October 31, 2025

Key Takeaways Effectively treating Alzheimer’s disease has been one of the most significant failures of the pharmacological industry.  Yet Alzheimer’s can be viewed as a metabolic…

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Categories: Alzheimers Disease, Latest News

What Really Causes Obesity? The Role of Metabolism, Insulin Resistance, and AMPK

  • Barry Sears
  • Estimated read time 7 min read
  • September 23, 2025

Key Takeaways There is no doubt that obesity is on the rise.  But why?  Is it because we are not exercising enough? Or are we simply…

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Categories: Latest News, Obesity

Long COVID and Metabolism: How AMPK Activation May Reduce Risk

  • Barry Sears
  • Estimated read time 7 min read
  • September 23, 2025

Key Takeaways It has been nearly five years since COVID-19 first appeared.  However, for many, the consequences of initial infection remain with them for years.  About…

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Categories: Latest News, Metabolic Engineering®

What Causes Leaky Gut? The Role of AMPK in Gut Barrier Health

  • Barry Sears
  • Estimated read time 8 min read
  • August 5, 2025

Key Takeaways What Is Metabolic Endotoxemia? People are obsessed with gut health.  They should be, because without a healthy gut, you would be a sitting target…

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Categories: Gut Health, Latest News

Stopping GLP-1 Drugs: Why Weight Regain May Increase Heart Disease Risk

  • Barry Sears
  • Estimated read time 10 min read
  • July 29, 2025

Key Takeaways Everyone wants to lose excess body fat.  However, the Holy Grail of weight loss is losing excess body fat while maintaining, if not increasing,…

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Categories: GLP-1 Drugs, Heart Disease, Latest News
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